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BM635 (hydrochloride)

CAT: 0804-HY-109587ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-109587ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BM635 hydrochloride is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC50 of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635[1].
CAS Number
2748337-90-6
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bm635-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(C2=CC(CN3CCOCC3)=C(C)N2C4=CC=C(F)C=C4)C=C1)C.[H]Cl
Molecular Formula
C25H30ClFN2O
Molecular Weight
428.97
References & Citations
[1]Poce G, et al. Pharmaceutical salt of BM635 with improved bioavailability. Eur J Pharm Sci. 2017 Mar 1;99:17-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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