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Clotrimazole-d5

CAT: 0804-HY-10882SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10882SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Clotrimazole-d5 is the deuterium labeled Clotrimazole. Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity[1][2].
CAS Number
1185076-41-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Autophagy; Bacterial; Fungal; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Autophagy; Others
Field of Research
Infection; Cancer
Purity
99.47
Solubility
10 mM in DMSO
Smiles
ClC(C=CC=C1)=C1C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])(C3=CC=CC=C3)N4C=CN=C4
Molecular Formula
C22H12D5ClN2
Molecular Weight
349.87
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Schaller K. In vitro antibacterial activity of different clotrimazole formulations. Chemotherapy. 1982;28 Suppl 1:32-6.|[3]Sawyer PR, Clotrimazole: a review of its antifungal activity and therapeutic efficacy. Drugs. 1975;9 (6) :424-47.|[4]Witzke A, Inhibition of the gastric H, K-ATPase by clotrimazole. Biochemistry. 2010 Jun 1;49 (21) :4524-32.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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