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Clotrimazole

CAT: 0804-HY-10882-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10882-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.
CAS Number
23593-75-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H410
Target
Antibiotic; Autophagy; Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Clotrimazole.html
Purity
99.91
Solubility
DMSO : 33.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
ClC1=CC=CC=C1C(N2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4
Molecular Formula
C22H17ClN2
Molecular Weight
344.84
Precautions
H302, H315, H319, H410
References & Citations
[1]Sawyer PR, Clotrimazole: a review of its antifungal activity and therapeutic efficacy. Drugs. 1975;9 (6) :424-47.|[2]Witzke A, Inhibition of the gastric H, K-ATPase by clotrimazole. Biochemistry. 2010 Jun 1;49 (21) :4524-32.|[3]Schaller K. In vitro antibacterial activity of different clotrimazole formulations. Chemotherapy. 1982;28 Suppl 1:32-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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