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Defibrotide (sodium)

CAT: 0804-HY-108746-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-108746-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Defibrotide sodium is a complex mixture of single stranded polydeoxyribonucleotides. Defibrotide sodium has liver protection, anti-inflammatory, antithrombotic, profibrinolytic, and anti-ischemic properties. Defibrotide sodium can be used for sinusoidal obstruction syndrome (SOS) /veno-occlusive disease (VOD) research[1].
CAS Number
83712-60-1
UNSPSC
12352208
Target
Others
Type
Oligonucleotides
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/defibrotide-sodium.html
Purity
90.00
Solubility
10 mM in H2O
Smiles
[Defibrotide(sodium)]
Molecular Weight
13-20 (KDa)
References & Citations
[1]May T Aziz, et al. Defibrotide: An Oligonucleotide for Sinusoidal Obstruction Syndrome. Ann Pharmacother. 2018 Feb;52 (2) :166-174.|[2]W Paul, et al. The effect of defibrotide on thromboembolism in the pulmonary vasculature of mice and rabbits and in the cerebral vasculature of rabbits. Br J Pharmacol. 1993 Dec;110 (4) :1565-71.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Oligonucleotides
Clinical Information
Launched