Defibrotide (sodium)

• UNSPSC Description:

  Defibrotide sodium is a complex mixture of single stranded polydeoxyribonucleotides. Defibrotide sodium has liver protection, anti-inflammatory, antithrombotic, profibrinolytic, and anti-ischemic properties. Defibrotide sodium can be used for sinusoidal obstruction syndrome (SOS)/veno-occlusive disease (VOD) research[1].

• Target Antigen:

  Others

• Type:

  Oligonucleotides

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/defibrotide-sodium.html

• Solubility:

  10 mM in H2O

• Smiles:

  [Defibrotide (sodium)]

• References & Citations:

  [1]May T Aziz, et al. Defibrotide: An Oligonucleotide for Sinusoidal Obstruction Syndrome. Ann Pharmacother. 2018 Feb;52(2):166-174.|[2]W Paul, et al. The effect of defibrotide on thromboembolism in the pulmonary vasculature of mice and rabbits and in the cerebral vasculature of rabbits. Br J Pharmacol. 1993 Dec;110(4):1565-71.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  83712-60-1