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CDP-840

CAT: 0804-HY-108620Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-108620Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDP-840 (GR259653X) is a potent, selective and orally active phosphodiesterase IV (PDE IV) inhibitor. CDP-840 inhibits antigen-induced early and late phase bronchoconstriction in conscious squirrel monkeys[1].
CAS Number
[162542-90-7]
Product Name Alternative
GR259653X
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cdp-840.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C([C@@H](C2=CC=CC=C2)CC3=CC=NC=C3)C=C1OC4CCCC4
Molecular Formula
C25H27NO2
Molecular Weight
373.49
References & Citations
[1]Jones TR, et al. Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma. Can J Physiol Pharmacol. 1998 Feb;76 (2) :210-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PDE4

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