BMS-193885 (L-Lactic acid)

BMS-193885 (L-Lactic acid)

• CAS Number: 679839-66-8
• UNSPSC Description: BMS-193885 (L-Lactic acid) is a potent, selective, and brain-penetrant neuropeptide Y1 receptor antagonist. BMS-193885 has a Ki value of 3.3 nM for the neuropeptide Y1 receptor, competitively acts on the neuropeptide Y binding site, and can reduce food intake and body weight through central Y1 inhibition[1].
• Target Antigen: Neuropeptide Y Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/bms-193885-l-lactic-acid.html
• Solubility: 10 mM in DMSO
• Smiles: COC(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC(NC(NCCCN3CCC(C4=CC(OC)=CC=C4)CC3)=O)=CC=C2)=O.OC([C@@H](O)C)=O
• Molecular Weight: 680.79
• References & Citations: [1]Ildiko Antal-Zimanyi, et al. Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist. Eur J Pharmacol. 2008 Aug 20;590(1-3):224-32.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported