Ro 8-4304 (hydrochloride)

• UNSPSC Description:

  Ro 8-4304 hydrochloride is a potent NMDA receptor antagonist. Ro 8-4304 hydrochloride is a NR2B selective, non-competitive, voltage-independent antagonist[1].

• Target Antigen:

  iGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ro-8-4304-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC(C(C=C1)=CC=C1OCC(O)CN2CCC(C3=CC=C(F)C=C3)=CC2)=O.Cl

• Molecular Weight:

  406.88

• References & Citations:

  [1]Kew JN, et, al. State-dependent NMDA receptor antagonism by Ro 8-4304, a novel NR2B selective, non-competitive, voltage-independent antagonist. Br J Pharmacol. 1998 Feb;123(3):463-72.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1312991-77-7