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FXa-IN-1

CAT: 0804-HY-10758Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-10758Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FXa-IN-1 is a FXa inhibitor (IC50: 3 nM, Ki: 0.7 nM) with respectable oral bioavailability and half-life in vivo. FXa-IN-1 can be used for thromboembolic disorders[1].
CAS Number
441328-10-5
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fxa-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C(N(C)C)=N)C=C1F)C2=CC(C(F)(F)F)=NN2C3=C(F)C=C(C=CC=C4)C4=C3
Molecular Formula
C24H18F5N5O
Molecular Weight
487.42
References & Citations
[1]Zhaozhong J Jia, et al. 1- (2-Naphthyl) -1H-pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 3: Design, synthesis and SAR of orally bioavailable benzamidine-P4 inhibitors. Bioorg Med Chem Lett. 2004 Mar 8;14 (5) :1229-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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