(±) -HIP-B

CAT: 0804-HY-107524Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-107524Size:1 Each

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Description

(±) -HIP-B is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM) . (±) -HIP-B is also a lead compound against ischemia-induced neuronal degeneration. (±) -HIP-B can be used in the study of neurological diseases[1].

CAS Number

227619-65-0

UNSPSC

12352005

Target

EAAT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/racemic-hip-b.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H]1[C@]2([H])[C@@](CN1)([H])C(NO2)=O)=O

Molecular Formula

C6H8N2O4

Molecular Weight

172.14

References & Citations

[1]Andrea Pinto, et al. Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Catalog	Name
T22480-01	(±) -HIP-B
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B6983-10	(±)-HIP-B
MBS5756984	(+/-)-HIP-B
255451	(±) -HIP-B discontinued
B6982-10	(±)-HIP-A
MBS5756983	(+/-)-HIP-A
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(±) -HIP-B

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