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Uridine triphosphate-d13 (dilithium)

CAT: 0804-HY-107372S3Size: 1 mg (100 mM in 19.64 μL Tris HCl/D2O buffer pH=7.5)Dry Ice: NoHazardous: No
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CAT#:0804-HY-107372S3Size:1 mg (100 mM in 19.64 μL Tris HCl/D2O buffer pH=7.5)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Uridine triphosphate-d13 (UTP-d13 dilithium; Uridine 5'-triphosphate-d13) dilithium is deuterium labeled Uridine triphosphate. Uridine triphosphate (UTP; Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.
Product Name Alternative
UTP-d13 (dilithium) ; Uridine 5'-triphosphate-d13 (dilithium)
UNSPSC
12352005
Target
DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Concentration
100 mM in 19.64 μL Tris HCl/D2O buffer pH=7.5
Purity
99.6
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@]2([2H])[C@](O[2H])([2H])[C@@](O[2H])([2H])[C@](C([2H])([2H])OP(O[2H])(OP(OP(O[2H])(O[Li])=O)(O[Li])=O)=O)([2H])O2)N([2H])C(C([2H])=C1[2H])=O
Molecular Formula
C9D13Li2N2O15P3
Molecular Weight
509.09
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Lamarca A, et al. Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation. PLoS One. 2014 Jun 6;9 (6) :e98998.|[3]Choi JH, et al. Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor. Pancreas. 2013 May;42 (4) :680-6.|[4]Yitzhaki S, et al. Uridine-5'-triphosphate (UTP) reduces infarct size and improves rat heart function aftermyocardial infarct. Biochem Pharmacol. 2006 Oct 16;72 (8) :949-55.|[5]Iwaki Y, et al. Enhancement of antibody production against rabies virus by uridine 5'-triphosphate in mice. Microbes Infect. 2014 Mar;16 (3) :196-202.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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