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F-1394

CAT: 0804-HY-106902-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106902-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
F-1394 is an orally active acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor that inhibits dietary cholesterol absorption in mice. F-1394 can be used in cardiovascular disease research[1].
CAS Number
162490-89-3
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/f-1394.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCN(CC(C)(C)C)C(N[C@@H](CCCC1)[C@H]1OC(CCNC([C@H]2C(C)(COC(C)(C)O2)C)=O)=O)=O
Molecular Formula
C33H61N3O6
Molecular Weight
595.85
References & Citations
[1]Kusunoki J, et al. Hypocholesterolemic action and prevention of cholesterol absorption via the gut by F-1394, a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, in cholesterol diet-fed rats. Jpn J Pharmacol. 1995 Sep;69 (1) :53-60. |[2]Kusunoki J, et al. Hypocholesterolemic action and prevention of cholesterol absorption via the gut by F-1394, a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, in cholesterol diet-fed rats. Jpn J Pharmacol. 1995 Sep;69 (1) :53-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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