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(E) -Ajoene

CAT: 0804-HY-106784ASize: 1 mg (42.66 mM x 100 μL in Ethyl Acetate)Dry Ice: NoHazardous: No
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CAT#:0804-HY-106784ASize:1 mg (42.66 mM x 100 μL in Ethyl Acetate)
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Description
(E) -Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E) -Ajoene has been proved to show neuroprotective effects against ischemic damage. (E) -Ajoene is orally active to inhibit lipid peroxidation. (E) -Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region[1][2].
CAS Number
92284-99-6
UNSPSC
12352100
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e-ajoene.html
Concentration
42.66 mM * 100 μL in Ethyl acetate
Purity
95
Solubility
10 mM in DMSO
Smiles
O=S(C/C=C/SSCC=C)CC=C
Molecular Formula
C9H14OS3
Molecular Weight
234.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Rakshit D, et al. The Pharmacological Activity of Garlic (Allium sativum) in Parkinson's Disease: From Molecular Mechanisms to the Therapeutic Potential. ACS Chem Neurosci. 2023 Mar 15;14 (6) :1033-1044. |[2]Yoo DY, et al. Neuroprotective effects of Z-ajoene, an organosulfur compound derived from oil-macerated garlic, in the gerbil hippocampal CA1 region after transient forebrain ischemia. Food Chem Toxicol. 2014 Oct;72:1-7.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported