BTG 1640

• Description :

  BTG 1640 (ABIO-08/01) is a potent anxiolytic isoxazoline. BTG 1640 is a selective inhibitor of GABA- and glutamate-gated chloride channels[1].

• Product Name Alternative :

  ABIO-08/01

• UNSPSC :

  12352005

• Target :

  Chloride Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/btg-1640.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN1[C@H]([C@]2([H])[C@](CCCC2=O)([H])O1)CC3=CC=CC=C3

• Molecular Formula :

  C15H19NO2

• Molecular Weight :

  245.32

• References & Citations :

  [1]Correll CU, et al. The future of psychopharmacology: a critical appraisal of ongoing phase 2/3 trials, and of some current trends aiming to de-risk trial programmes of novel agents. World Psychiatry. 2023 Feb;22 (1) :48-74.|[2]Saletu-Zyhlarz GM, et al. Double-blind, placebo-controlled, multiple-ascending-dose study on the pharmacodynamics of ABIO-08/01, a new CNS drug with potential anxiolytic activity. 1. EEG mapping, psychometric and tolerability findings. Neuropsychobiology. 2009;59 (2) :100-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [152538-59-5]