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Tropatepine

CAT: 0804-HY-105710-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:HY-105710-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tropatepine is an orally active, anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic agents[2].
CAS Number
[27574-24-9]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tropatepine.html
Purity
99.63
Solubility
10 mM in DMSO
Smiles
CN1[C@@H]2C/C(C[C@H]1CC2)=C3C4=CC=CC=C4SCC5=CC=CC=C\35
Molecular Formula
C22H23NS
Molecular Weight
333.49
References & Citations
[1]P Celsis, et al. Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1989 Jul;52 (7) :917-8.|[2]P Arnoux, et al. Simultaneous determination of tropatepine and its major metabolites by high-performance liquid chromatographic-mass spectrometric identification. Application to metabolic and kinetic studies. J Chromatogr. 1986 Aug 22;381 (1) :75-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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