Tropatepine

• Description :

  Tropatepine is an orally active, anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic agents[2].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/tropatepine.html

• Purity :

  99.63

• Solubility :

  10 mM in DMSO

• Smiles :

  CN1[C@@H]2C/C(C[C@H]1CC2)=C3C4=CC=CC=C4SCC5=CC=CC=C\35

• Molecular Formula :

  C22H23NS

• Molecular Weight :

  333.49

• References & Citations :

  [1]P Celsis, et al. Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1989 Jul;52 (7) :917-8.|[2]P Arnoux, et al. Simultaneous determination of tropatepine and its major metabolites by high-performance liquid chromatographic-mass spectrometric identification. Application to metabolic and kinetic studies. J Chromatogr. 1986 Aug 22;381 (1) :75-82.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [27574-24-9]