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FR 113680

CAT: 0804-HY-105436Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-105436Size:1 Each
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Description
FR 113680 is a tripeptide substance P antagonist that interacts selectively with the NK1 neurokinin receptor[1].
CAS Number
[126088-92-4]
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fr-113680.html
Solubility
10 mM in DMSO
Smiles
CN(CC1=CC=CC=C1)C([C@H](CC2=CC=CC=C2)NC([C@H](NC([C@H]([C@H](O)C)NC(C)=O)=O)CC3=CN(C=O)C4=C3C=CC=C4)=O)=O
Molecular Formula
C35H39N5O6
Molecular Weight
625.71
References & Citations
[1]Morimoto H, et al. FR 113680: a novel tripeptide substance P antagonist with NK1 receptor selectivity. Br J Pharmacol. 1992 May;106 (1) :123-6.|[2]Morimoto H, et al. Effects of FR 113680 and FK 224, novel tachykinin receptor antagonists, on cigarette smoke-induced rat tracheal plasma extravasation. Eur J Pharmacol. 1992 Nov 24;224 (1) :1-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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