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Mesulergine (hydrochloride)

CAT: 0804-HY-103147-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103147-01Size:5 mg
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Description
Mesulergine (CU32-085) hydrochloride is a potent 5-HT2C antagonist and dopamine (DA) agonist. Mesulergine hydrochloride presentes hyperphagia. Mesulergine hydrochloride has the potential for the research of cognitive processes[1][2].
CAS Number
72786-12-0
Product Name Alternative
CU32-085 (hydrochloride)
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mesulergine-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CN1C2=C3C([C@]4([H])[C@@](N(C[C@H](C4)NS(N(C)C)(=O)=O)C)([H])CC3=C1)=CC=C2.Cl
Molecular Formula
C18H27ClN4O2S
Molecular Weight
398.95
References & Citations
[1]Giannakopoulos G, et al. Effects of mesulergine treatment on diet selection, brain serotonin (5-HT) and dopamine (DA) turnover in free feeding rats. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Jul;22 (5) :803-13. |[2]Khaliq S, et al. Influence of serotonergic 5-HT2C receptor antagonist mesulergine in the reversal of memory deficits induced by mCPP. J Coll Physicians Surg Pak. 2012 Feb;22 (2) :75-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; Dopamine Receptor; α-1 microglobulin