(R)-SCH 42495

• UNSPSC Description:

  (R)-SCH 42495 is the less active enantiomer of SCH 42495[1]. SCH 42495 is an orally active neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally active ethylester proagent of SCH 42354[2].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/r-sch-42495.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CSCC[C@@H](C(OCC)=O)NC([C@H](CSC(C)=O)CC1=CC=CC=C1C)=O

• Molecular Weight:

  411.58

• References & Citations:

  [1]Neustadt BR, et al. Mercaptoacyl amino acid inhibitors of atriopeptidase. 1. Structure-activity relationship studies of methionine and S-alkylcysteine derivatives. J Med Chem. 1994 Jul 22;37(15):2461-76.|[2]Watkins RW, et al. Atrial natriuretic factor potentiating and hemodynamic effects of SCH 42495, a new, neutral metalloendopeptidase inhibitor. Am J Hypertens. 1993 May;6(5 Pt 1):357-68.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  156792-25-5