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10-Nitrooleate-d17 (nitrate)

CAT: 0804-HY-101559SSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-101559SSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
10-Nitrooleate-d17 (nitrate) is the deuterium labeled 10-Nitrooleic acid nitrate. 10-Nitrooleic acid (CXA-10) nitrate, a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles[1].
CAS Number
2749984-40-3
UNSPSC
12352211
Hazard Statement
H225-H319
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])(/C([N+]([O-])=O)=C\CCCCCCCC(O)=O)C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H]
Molecular Formula
C18H16D17NO4
Molecular Weight
344.56
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Garner RM, Mould DR, Chieffo C, Jorkasky DK. Pharmacokinetic and Pharmacodynamic Effects of Oral CXA-10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects. Clin Transl Sci. 2019;12 (6) :667-676. |[3]Zheng R, et al. Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid. Free Radic Biol Med. 2014;67:1-9.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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