Harmane (Standard)

• UNSPSC Description:

  Harmane (Standard) is the analytical standard of Harmane. This product is intended for research and analytical applications. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively). Harmane exhibits comutagenic effect[1][2][3][4].

• Target Antigen:

  Adrenergic Receptor; Imidazoline Receptor; Monoamine Oxidase

• Type:

  Reference Standards

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Cancer; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/harmane-standard.html

• Smiles:

  CC1=NC=CC2=C1NC3=C2C=CC=C3

• Molecular Weight:

  182.22

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  486-84-0