Harmane (Standard)

CAT: 0804-HY-101392R-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-101392R-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Harmane (Standard) is the analytical standard of Harmane. This product is intended for research and analytical applications. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM) . Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively) . Harmane exhibits comutagenic effect[1][2][3][4].
CAS Number
[486-84-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Adrenergic Receptor; Imidazoline Receptor; Monoamine Oxidase; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/harmane-standard.html
Smiles
CC1=NC=CC2=C1NC3=C2C=CC=C3
Molecular Formula
C12H10N2
Molecular Weight
182.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B; α adrenergic receptor

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