(+)-N-Allylnormetazocine (hydrochloride)

(+)-N-Allylnormetazocine (hydrochloride)

• CAS Number: 133005-41-1
• UNSPSC Description: (+)-N-Allylnormetazocine ((+)-SKF 10047) hydrochloride is a benzomorphan opioid with psychotomi metic effects. (+)-N-Allylnormetazocine hydrochloride is an opioid receptor antagonist with Ki values of 300 nM and 27 μM for σ1 and σ2 opioid receptors, respectively. (+)-N-Allylnormetazocine hydrochloride can be used for the research of neurological disease[1][2].
• Target Antigen: Opioid Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/plus-n-allylnormetazocine-hydrochloride.html
• Purity: 99.0
• Solubility: H2O : 100 mg/mL (ultrasonic)
• Smiles: C[C@@]1(CCN2CC=C)C3=CC(O)=CC=C3C[C@@]2([H])C1([H])C.Cl
• Molecular Weight: 293.83
• References & Citations: [1]May EL, et al. Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2'-hydroxy-6,7-benzomorphan homologues. J Med Chem. 2000 Dec 28;43(26):5030-6.|[2]Brady KT, et al. Stereoisomers of N-allylnormetazocine: phencyclidine-like behavioral effects in squirrel monkeys and rats. Science. 1982 Jan 8;215(4529):178-80.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, stored under nitrogen, away from moisture)
• Clinical Information: No Development Reported