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Clocinnamox (mesylate)

CAT: 0804-HY-101306Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-101306Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
117332-69-1
UNSPSC Description
Clocinnamox (mesylate) is a potent opioid antagonist acting at mu, kappa and delta-receptors. Clocinnamox is a selective mu-receptor antagonist than kappa and delta-receptors[1].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/clocinnamox-mesylate.html
Solubility
10 mM in DMSO
Smiles
OC1=C(O2)C([C@]([C@@H]2C(CC3)=O)(CCN4CC5CC5)[C@]3(NC(/C=C/C6=CC=C(Cl)C=C6)=O)[C@H]4C7)=C7C=C1.CS(=O)(O)=O
Molecular Weight
601.11
References & Citations
[1]S D Comer, et, al. Clocinnamox: a novel, systemically-active, irreversible opioid antagonist. J Pharmacol Exp Ther. 1992, 262, 3.|[2]E R Butelman, et, al. Clocinnamox antagonism of opioid suppression of schedule-controlled responding in rhesus monkeys. Psychopharmacology (Berl). 1996, 123, 4.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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