MTPG

CAT: 0804-HY-101247Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-101247Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1].

CAS Number

169209-66-9

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mtpg.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C(C)(N)C1=CC=C(C2=NN=NN2)C=C1

Molecular Formula

C10H11N5O2

Molecular Weight

233.23

References & Citations

[1]Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404 (1-2) :182-186.|[2]Feng RF, Li WB, Liu HQ, et al. Sheng Li Xue Bao. 2003;55 (3) :303-310.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-155785	MTP
HY-173469	MTP3 ligand-1
HY-173467	PROTAC MTP3 degrader-1
HY-173470	MTP3 Ligand-linker Conjugate 1
HY-RS08814	MTPN Human Pre-designed siRNA Set A

Alternative Products

Catalog	Name
255917-01	MTPG

MTPG

Related Products

Alternative Products

Popular Products