Products for Research Use Only
RegisterLogin

CD25 Antibody / IL2RA

CAT: 0013-GTR18083066-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18083066-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Recognizes a protein of 55kDa, identified as CD25 (Workshop IV; Code A27) . CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.
UniProt
P01589
Reactivity
Human
Immunogen
Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
Clonality
Monoclonal
Clone
IL2RA/2393
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
ELISA: order Ab without BSA for coating
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CD25 antibody should be determined by the researcher.
Tested Applications
ELISA
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG2b, kappa

UniProtKB · P01589

Interleukin-2 receptor subunit alpha

IL2RA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01589
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL2RA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA
EC number
—
Processing
Precursor
Secondary accessions
Q5W007
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Diabetes mellitusDisease variant

PTM

Disulfide bondGlycoprotein

Biological process

Immunity

Cellular component

Membrane

Molecular function

Receptor

Domain

RepeatSignalSushiTransmembraneTransmembrane helix

Related Products

CatalogName
GTR18225893IL2RA/CD25 Antibody
GTR18568256CD25 (IL2RA) Antibody
GTR18125344CD25/IL2RA Antibody
GTR18915624CD25 / IL2RA Peptide
GTR17721592-01IL2RA/CD25 Rabbit Polyclonal Antibody
GTR18696980-01CD25/IL2RA Human Monoclonal Antibody
GTR18777695-01Human CD25/IL2RA Monoclonal Antibody
GTR18777518-01InVivoMAb Mouse CD25/IL2RA Antibody
GTR18711931IL2RA/CD25 Mouse mAb Antibody
GTR18336896-01IL2RA/CD25 Mouse Monoclonal Antibody

Alternative Products

CatalogName
RQ4974CD25 Antibody / IL2RA
R30839IL2RA Antibody / CD25
43-525CD25 / IL2RA Antibody
STJ16101100Anti-CD25/IL2RA antibody
ANT-10997-50ugCD25 / IL2RA Monoclonal Antibody
bs-0577R-01IL2RA/CD25 Polyclonal Antibody
E55A15513Human CD25/IL2RA Antibody
E55A06238Mouse CD25/IL2RA Antibody
bsm-33113MIL2RA/CD25 monoclonal antibody
E55A04657CD25/IL2RA Polyclonal Antibody

Popular Products