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Bcl-X Antibody

CAT: 0013-GTR18082950-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18082950-01Size:20 µg
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Description
Recognizes a protein of 27kDa, identified as the Bcl-X protein. This MAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2.
UniProt
Q07817
Reactivity
Human
Immunogen
A recombinant human partial protein (amino acids 1-135) was used as the immunogen for this Bcl-X antibody.
Clonality
Monoclonal
Clone
SPM519
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Bcl-X antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG

UniProtKB · Q07817

Bcl-2-like protein 1

B2CL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q07817
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BCL2L1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Bcl2-L-1
EC number
—
Processing
—
Secondary accessions
E1P5L6, Q5CZ89, Q5TE65, Q92976
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisEndocytosis

Cellular component

CytoplasmCytoplasmic vesicleCytoskeletonMembraneMitochondrionMitochondrion inner membraneMitochondrion outer membraneNucleusSynapse

PTM

PhosphoproteinUbl conjugation

Domain

TransmembraneTransmembrane helix

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