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Recombinant SOX2 Antibody

CAT: 0013-GTR18082585-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18082585-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity) . Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity) . Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. [UniProt]
UniProt
P48431
Reactivity
Human
Immunogen
Amino acids 176-305 were used as the immunogen for the recombinant SOX2 antibody.
Clonality
Recombinant
Clone
SBX2-1R
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein A affinity chromatography
Dilution
ELISA (order BSA-free format for coating), Western blot: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The stated application concentrations are suggested starting points. Titration of the SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Tested Applications
IHC-P, WB
Host or Source
Rabbit
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Rabbit IgG, kappa

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