Products for Research Use Only
RegisterLogin

GITR Antibody (TNFRSF18)

CAT: 0013-GTR18081553-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18081553-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GITR (glucocorticoid-induced TNFR-related gene) is a member of the TNF-receptor superfamily, also known as TNFRSF18. It is expressed at low levels on resting T lymphocytes and at high levels on CD25+ CD4+ Tregs. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production as well as MAPKs and NF-kB activation, and abrogate the inhibitory function of CD25+ CD4+ Tregs. In vivo activation of GITR causes development of autoimmune diseases and restores the suppressed immune response.
UniProt
O35714
Reactivity
Mouse
Immunogen
Mouse CD25+ CD4+ T cells were used as the immunogen for the GITR antibody.
Clonality
Monoclonal
Clone
DTA-1
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein G affinity chromatography
Dilution
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 0.5-1ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the GITR antibody should be determined by the researcher.
Tested Applications
FACS, IF
Host or Source
Rat
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Rat IgG2b, lambda

Related Products

CatalogName
GTR18225742TNFRSF18/GITR Antibody
GTR18311844-01TNFRSF18/GITR/CD357 Antibody
GTR18912028GITR / TNFRSF18 Recombinant Protein
GTR18315288TNFRSF18 / GITR / CD357 Reference Antibody
GTR17694368GITR/Tnfrsf18 Rabbit Polyclonal Antibody
GTR18776594-01Human CD357/TNFRSF18/GITR Antibody
GTR18311587-01TNFRSF18 / GITR / CD357 Reference Antibody
GTR18776593-01Human CD357/TNFRSF18/GITR Antibody
GTR18757017GITR/Tnfrsf18 Rabbit Polyclonal Antibody (Fluoro488)
GTR18696924-01CD357/TNFRSF18/GITR Human Monoclonal Antibody

Alternative Products

CatalogName
V3050SAF-100UGGITR Antibody (TNFRSF18)
RQ4383GITR Antibody / TNFRSF18
V8185SAF-100UGTNFRSF18 Antibody / GITR
MBS1753067-01Anti-GITR/Tnfrsf18 Antibody
MBS2565340-01GITR/TNFRSF18 Polyclonal Antibody
E55A06123Human CD357/TNFRSF18/GITR Antibody
TMAY-02614Anti-GITR/TNFRSF18 Antibody (8R877)
ANT-11168-100ugCD357 / TNFRSF18 / GITR Monoclonal Antibody
A03125-3Anti-GITR/Tnfrsf18 Picoband® Antibody
HY-P990525Anti-TNFRSF18/GITR/CD357 Antibody

Popular Products