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CRHR2 Antibody

CAT: 0013-GTR18080845-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18080845-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CHCR2, or Corticotropin releasing hormone receptor 2, is a receptor for CRH (corticotropin-releasing hormone), a neurotransmitter secreted by the hypothalamus in response to stress. There are three major isoforms of CHCR2: alpha, beta and gamma, differing in their N-terminus amino acid sequence. Isoform beta and gamma are expressed in the brain, with gamma expression highest in the septum and hippocampus, while alpha is expressed in the peripheral tissues of the brain.
UniProt
Q13324
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant protein fragment from the N-terminal portion of human CRHR2 was used as the immunogen for this antibody (1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics, GPCR, Neuroscience, Signaling Pathways
Purification
Protein A affinity chromatography
Dilution
Western blot: 0.5-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Provided assay concentrations are suggestions only, CRHR2 antibody titration may be required for optimal results.1. This antibody will detect the alpha (411 AA), beta (438 AA) and gamma (397 AA) isoforms of CRHR2.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG

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