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Mitofusin 2 Antibody

CAT: 0013-GTR18080407Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18080407Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse Anti-Human Mitofusin 2 Monoclonal IgG2a
Product Name Alternative
Mitofusin 2, MFN2, Mfn2, Mitofusin-2, Transmembrane GTPase MFN2, Mitochondrial assembly regulatory factor, MARF, CMT2A, CMT2A2, CPRP1, CPRP 1, Fzo, HSG, Hyperplasia suppressor gene, Hypertension related protein 1, KIAA0214
UniProt
Q80U63
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2. Rat: 97% identity (226/231 amino acids identical) . Human: 92% identity (214/231 amino acids identical) ~55% identity with Mitofusin-1.
Target
Mitofusin 2
Clonality
Monoclonal
Clone
N153/5 (Formerly sold as S153-5)
Conjugation
Unconjugated
Field of Research
Cancer Biology, Cell Biology, Disease Biomarkers, Neuroscience, Signal Transduction
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), ICC/IF (1:100)
Molecular Weight
90kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Mitofusin-2 in 20 μg of mouse cardiac mitochondrial lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_573464.2
Host or Source
Mouse
Preservative
PBS pH 7.4, 50% glycerol, 0.1% sodium azide. Storage buffer changes when conjugated.
Isotype
IgG2a
Entrez
170731

UniProtKB · Q80U63

Mitofusin-2

MFN2_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q80U63
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Mfn2
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
3.6.5.-
Processing
—
Secondary accessions
A2A7Y7, A8Y5E4, Q3V3B8, Q80WP4, Q80XK3, Q8BHF0, Q8BKV5, Q8R535, Q923X2
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisAutophagyUnfolded protein response

Domain

Coiled coilTransmembraneTransmembrane helix

Molecular function

Developmental proteinHydrolase

Technical term

Direct protein sequencingReference proteome

Ligand

GTP-bindingNucleotide-binding

Cellular component

MembraneMitochondrionMitochondrion outer membrane

PTM

PhosphoproteinUbl conjugation

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