NS2B/NS3-IN-2
CAT:
804-HY-144612-06
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NS2B/NS3-IN-2
- CAS Number: 3010940-08-3
- UNSPSC Description: NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 μM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate[1].
- Target Antigen: Dengue virus; Flavivirus; Virus Protease
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/ns2b-ns3-in-2.html
- Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=S(C(C=C1)=CC=C1OCC)(N2N=C(C=C2N)OC(C3=CC=C(C=C3)C4=CC=CC=C4)=O)=O
- Molecular Weight: 463.51
- References & Citations: [1]Lin X,et al. Identification and In Silico Binding Study of a Highly Potent DENV NS2B-NS3 Covalent Inhibitor. ACS Med Chem Lett. 2022; 13(4):599-607.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported