dsDNA Recombinant Antibody / Double Stranded DNA

dsDNA Recombinant Antibody / Double Stranded DNA

• Description: This mAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This mAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.
• CAS Number: 9000-83-3
• UniProt: Not Applicable
• Host: Mouse
• Immunogen: Burkitt's cell nuclei were used as the immunogen for the Double Stranded DNA antibody.
• Clonality: Monoclonal
• Isotype: IgG2b κ
• Type: Recombinant
• Applications: IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Aliquot the Double Stranded DNA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This Double Stranded DNA antibody is available for research use only.