PD-L1 Recombinant Antibody / B7-H1 / CD274

• Description:

  PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

• UniProt:

  Q9NZQ7

• Host:

  Rabbit

• Immunogen:

  A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the PD-L1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG κ

• Type:

  Recombinant

• Applications:

  IHC-P

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Aliquot the PD-L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This PD-L1 antibody is available for research use only.

• CAS Number:

  9000-83-3