VEGF Recombinant Antibody / Vascular Endothelial Growth Factor

• Description:

  This mAb recognizes proteins of 19-22kDa (reducing) and 38kDa-44kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

• UniProt:

  P15692

• Host:

  Rabbit

• Immunogen:

  A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the VEGF antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Type:

  Recombinant

• Applications:

  IHC-P

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Aliquot the VEGF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This VEGF antibody is available for research use only.

• CAS Number:

  9000-83-3