SDHB Recombinant Antibody / Succinate dehydrogenase B
CAT:
800-V4679-20UG
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SDHB Recombinant Antibody / Succinate dehydrogenase B
- Description: Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a key component of the citric acid cycle and the electron transport chain, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane.Many cancers are generally positive for SDHB, including renal cell carcinomas and gastrointestinal stromal tumors. A subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.
- UniProt: P21912
- Host: Mouse
- Immunogen: A recombinant partial protein sequence (within amino acids 180-280) from the human protein was used as the immunogen for the recombinant SDHB antibody.
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Type: Recombinant
- Applications: IHC-P
- Format: Purified
- Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
- Reconstitution: Aliquot the recombinant SDHB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This recombinant SDHB antibody is available for research use only.