TRPV3 Antibody

CAT: 0800-RQ7109Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0800-RQ7109Size:100 µg

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Description

Transient receptor potential cation channel, subfamily V, member 3, also known as TRPV3, is a human gene encoding the protein of the same name. This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

Q8NET8

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids VRRTDFNKIQDSSRNNSKTTLNAFEEVEEFPETSV were used as the immunogen for the TRPV3 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the TRPV3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This TRPV3 antibody is available for research use only.

Storage Conditions

After reconstitution, the TRPV3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the TRPV3 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) MDA-MB-453, 2) PC-3, 3) Caco-2 and 4) HeLa cell lysate with TRPV3 antibody. Predicted molecular weight ~90 kDa.

UniProtKB · Q8NET8

Transient receptor potential cation channel subfamily V member 3

TRPV3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q8NET8
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: TRPV3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: TrpV3
EC number: —
Processing: —
Secondary accessions: Q8NDW7, Q8NET9, Q8NFH2

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

ANK repeatRepeatTransmembraneTransmembrane helix

Ligand

CalciumMetal-bindingSodium

Molecular function

Calcium channelIon channel

Biological process

Calcium transportIon transportTransport

Cellular component

Cell membraneCytoplasmLysosomeMembrane

Disease

Disease variantPalmoplantar keratoderma

Product Datasheet

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