Products for Research Use Only

TLE1 Rabbit Monoclonal Antibody

CAT: 0013-GTR17693238Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR17693238Size:100 µL
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Description
TLE1 Rabbit Monoclonal Antibody
Product Name Alternative
Major prion protein; PrP; ASCR; PrP27-30; PrP33-35C; CD230; PRNP; ALTPRP, PRIP, PRP
UniProt
Q04724
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human TLE 1 Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling.
Target
Transducin-like enhancer protein 1
Clonality
Monoclonal
Clone
BCHGCX42
Conjugation
Unconjugated
Field of Research
Cell Biology, Neuroscience, Stem Cell & Developmental Biology
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Dilution
WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200
Form
Liquid
Molecular Weight
50 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IF, IHC, WB
Host or Source
Rabbit
Preservative
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG

UniProtKB · Q04724

Transducin-like enhancer protein 1

TLE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q04724
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TLE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K495, Q5T3G4, Q969V9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Nucleus

PTM

PhosphoproteinUbl conjugation

Domain

RepeatWD repeat

Molecular function

Repressor

Biological process

TranscriptionTranscription regulationWnt signaling pathway