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Cuspin-1

CAT: 0804-HY-119460-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119460-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cuspin-1 is a upregulator of Survival of Motor Neuron protein (SMN) . Cuspin-1 upregulates SMN expression post-transcriptionally, and increases the phosphorylation of Erk. Cuspin-1 can be used for research of neurodegenerative disease, such as spinal muscular atrophy (SMA) [1].
CAS Number
337932-29-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cuspin-1.html
Smiles
CC1=CC=C(C=C1)C(C2=CC(Br)=CN=C2)=O
Molecular Formula
C13H10BrNO
Molecular Weight
276.13
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Letso RR, et al. Small molecule screen reveals regulation of survival motor neuron protein abundance by Ras proteins. ACS Chem Biol. 2013 May 17;8 (5) :914-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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