Squarunkin A
CAT:
804-HY-127002-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Squarunkin A
- CAS Number: 2101958-02-3
- UNSPSC Description: Squarunkin A is a potent and selective UNC119-cargo interaction inhibitor, interrupting the UNC119A-myristoylated Src N-terminal peptide interaction (IC50=10 nM). Squarunkin A interferes with the activation of Src kinase in cells[1].
- Target Antigen: Src
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/squarunkin-a.html
- Purity: 99.34
- Solubility: DMSO : 9.62 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(N1CCC(NC2=C(NCCN3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3)C(C2=O)=O)CC1)OCC
- Molecular Weight: 523.55
- References & Citations: [1]Tom Mejuch, et al. Small-Molecule Inhibition of the UNC119-Cargo Interaction. Angew Chem Int Ed Engl. 2017 May 22;56(22):6181-6186.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported