Docusate (Sodium)

• UNSPSC Description:

  Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice[1][2].

• Target Antigen:

  HSV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/Docusate-Sodium.html

• Purity:

  98.0

• Solubility:

  H2O : ≥ 20 mg/mL

• Smiles:

  O=C(OCC(CC)CCCC)C(S(=O)(O[Na])=O)CC(OCC(CC)CCCC)=O

• Molecular Weight:

  444.56

• References & Citations:

  [1]Alexis M Temkin, et al. Increased adiposity, inflammation, metabolic disruption and dyslipidemia in adult male offspring of DOSS treated C57BL/6 dams. Sci Rep. 2019 Feb 6;9(1):1530.|[2]Y Gong, et al. Preclinical evaluation of docusate as protective agent from herpes simplex viruses. Antiviral Res. 2001 Oct;52(1):25-32.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  Launched

• CAS Number:

  577-11-7