Docusate (Sodium)

• Description :

  Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice[1][2].

• Product Name Alternative :

  Dioctyl sulfosuccinate (sodium salt)

• UNSPSC :

  12352100

• Hazard Statement :

  H315, H318

• Target :

  HSV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/Docusate-Sodium.html

• Purity :

  98.0

• Solubility :

  H2O : ≥ 20 mg/mL

• Smiles :

  O=C(OCC(CC)CCCC)C(S(=O)(O[Na])=O)CC(OCC(CC)CCCC)=O

• Molecular Formula :

  C20H37NaO7S

• Molecular Weight :

  444.56

• Precautions :

  H315, H318

• References & Citations :

  [1]Alexis M Temkin, et al. Increased adiposity, inflammation, metabolic disruption and dyslipidemia in adult male offspring of DOSS treated C57BL/6 dams. Sci Rep. 2019 Feb 6;9 (1) :1530.|[2]Y Gong, et al. Preclinical evaluation of docusate as protective agent from herpes simplex viruses. Antiviral Res. 2001 Oct;52 (1) :25-32.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  HSV-1; HSV-2

• CAS Number :

  [577-11-7]