N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)

N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)

• CAS Number: 2112737-60-5
• UNSPSC Description: N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n-t-boc-aminooxy-peg2-n-bis-peg3-propargyl.html
• Solubility: 10 mM in DMSO
• Smiles: C#CCOCCOCCOCCN(CCOCCOCCOCC#C)CCOCCOCCONC(OC(C)(C)C)=O
• Molecular Weight: 604.73
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported