Mianserin-d3 (hydrochloride)

• UNSPSC Description:

  Mianserin-d3 (hydrochloride) is the deuterium labeled Mianserin hydrochloride. Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

• Target Antigen:

  Histamine Receptor; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling;Others

• Field of Research:

  Neurological Disease; Endocrinology

• Solubility:

  10 mM in DMSO

• Smiles:

  [2H]C([2H])([2H])N1CC2N(CC1)C3=CC=CC=C3CC4=CC=CC=C42.Cl

• Molecular Weight:

  303.84

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Olianas MC,et al. The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors. Br J Pharmacol. 2012 Nov;167(6):1329-41.|[3]Roeder T. High-affinity antagonists of the locust neuronal octopamine receptor. Eur J Pharmacol. 1990 Nov 27;191(2):221-4.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1219804-97-3