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Bisaramil

CAT: 0804-HY-119092Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119092Size:1 Each
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Description
Bisaramil is an orally active antiarrhythmic agent. Bisaramil exerts concentration dependent inhibitory effect on PMA-stimulated free radical generation and prolonged the time lag concentration dependently[1][2].
CAS Number
89194-77-4
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bisaramil.html
Smiles
O=C(C1=CC=C(Cl)C=C1)O[C@]2([C@H]3CN(CC)C[C@@H]2CN(C)C3)[H]
Molecular Formula
C17H23ClN2O2
Molecular Weight
322.83
References & Citations
[1]M K Pugsley, et al. Effects of bisaramil, a novel class I antiarrhythmic agent, on heart, skeletal muscle and brain Na+ channels. Eur J Pharmacol. 1998 Jan 19;342 (1) :93-104.|[2]M Paróczai, et al. Bisaramil and antiarrhythmics as inhibitors of free radical generation. Pharmacol Res. 1997 Apr;35 (4) :279-85.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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T25157-01Bisaramil
BUP07796-01Bisaramil hydrochloride

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