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AH22921

CAT: 0804-HY-115827Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115827Size:1 Each
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Description
AH22921 is an EP4 prostaglandin receptor antagonist with the activity of antagonizing the activation of adenylate cyclase by prostaglandins in CHO cells. AH22921 can shift the PGE2 concentration-response curve to the right in CHO cells. It is a non-competitive antagonist that is selective for EP4 receptors and has an antagonistic effect on EP4 receptors in CHO cells, but does not affect the PGE2 concentration-response curve in NPE cells containing EP2 receptors.
CAS Number
74480-23-2
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ah22921.html
Smiles
OC(CCC/C=C/C[C@H]1[C@H](N2CCOCC2)C(C[C@H]1OCC3=CC=C(C4=CC=CC=C4)C=C3)=O)=O
Molecular Formula
C29H35NO5
Molecular Weight
477.59
References & Citations
[1]Endogenous EP4 prostaglandin receptors coupled positively to adenylyl cyclase in Chinese hamster ovary cells: pharmacological characterization
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T200553-01AH22921

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