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AH22921

CAT: 0931-T200553-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T200553-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
74480-23-2
Target
Prostaglandin Receptor, Others
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Others
Bioactivity
AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.
Smiles
C(/C=C\CCCC(O)=O)[C@H]1[C@@H](C(=O)C[C@H]1OCC2=CC=C(C=C2)C3=CC=CC=C3)N4CCOCC4
Molecular Formula
C29H35NO5
Molecular Weight
477.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-115827AH22921

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