Products for Research Use Only
RegisterLogin

PA452

CAT: 0804-HY-108522-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-108522-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PA452, retinoic X receptor (RXR) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development[1].
CAS Number
457657-34-0
UNSPSC
12352005
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pa452.html
Purity
99.0
Solubility
DMSO : 40 mg/mL (ultrasonic; warming) |Ethanol : 4.4 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=CN=C(N(C2=C(OCCCCCC)C=C3C(C)(C)CCC(C)(C)C3=C2)C)N=C1)O
Molecular Formula
C26H37N3O3
Molecular Weight
439.59
References & Citations
[1]Iwata M, et al. Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors. Int Immunol. 2003 Aug;15 (8) :1017-25.|[2]Varley CL, et al. Activation of peroxisome proliferator-activated receptor-gamma reverses squamous metaplasia and induces transitional differentiation in normal human urothelial cells. Am J Pathol. 2004 May;164 (5) :1789-98.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
BUP05584-01PA452

Popular Products