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Vesencumab

CAT: 0804-HY-P99386-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99386-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1) . Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer[1][2].
CAS Number
1205533-60-3
Product Name Alternative
MNRP-1685A
UNSPSC
12352203
Target
Complement System; EGFR; p38 MAPK; PDGFR
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vesencumab.html
Purity
99.89
Solubility
10 mM in DMSO
Smiles
[Vesencumab]
Molecular Weight
(145.262 kDa)
References & Citations
[1]Jonathan Stephens, et al. Rare disease landscape: will the blockbuster model be replaced? Expert Opinion on Orphan Drugs. Volume 2, 2014 - Issue 8. |[2]Zhang J, et al. Diabetic Macular Edema: Current Understanding, Molecular Mechanisms and Therapeutic Implications. Cells. 2022 Oct 25;11 (21) :3362.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1

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