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Podocarpusflavone A

CAT: 0804-HY-N2198-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2198-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Podocarpusflavone A is a DNA topoisomerase I inhibitor. Podocarpusflavone A has moderated anti-proliferative activity and induces cell apoptosis in MCF-7. Podocarpusflavone A is developing anti-tumor agents[1].
CAS Number
22136-74-9
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Apoptosis; Topoisomerase
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Podocarpusflavone-A.html
Purity
99.62
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(OC)C=C2)OC3=C(C4=CC(C5=CC(C6=C(O)C=C(O)C=C6O5)=O)=CC=C4O)C(O)=CC(O)=C13
Molecular Formula
C31H20O10
Molecular Weight
552.48
Precautions
H315, H319
References & Citations
[1]Pen-Ho Yeh et al. Naturally Occurring Cytotoxic [3′→8″]-Biflavonoids from Podocarpus nakaii J Tradit Complement Med. 2012 Jul;2 (3) :220-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Topo I

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