1-Methylisatin

CAT: 0804-HY-23148-01Size: 1 gDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-23148-01Size:1 g

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

1-Methylisatin is a potent and selective CE (carboxylesterases) inhibitor, with Kis of 38.2 and 5.38 μM for hiCE and hCE1, respectively. 1-Methylisatin interacts with Hb (human adult hemoglobin) by hydrophobic binding and electrostatic attraction. 1-Methylisatin can be used in the study of regulation of agent metabolism in vivo[1][2].

CAS Number

2058-74-4

Product Name Alternative

N-Methylisatin

UNSPSC

12352005

Hazard Statement

H301, H315, H318, H335

Target

Carboxylesterase (CES)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1-methylisatin.html

Purity

99.81

Solubility

DMSO : ≥ 125 mg/mL

Smiles

O=C1N(C)C2=C(C=CC=C2)C1=O

Molecular Formula

C9H7NO2

Molecular Weight

161.16

Precautions

H301, H315, H318, H335

References & Citations

[1]Hyatt JL, et al. Selective inhibition of carboxylesterases by isatins, indole-2,3-diones. J Med Chem. 2007 Apr 19;50 (8) :1876-85.|[2]Mandal P, et al. Fluorescence spectroscopic characterization of the interaction of human adult hemoglobin and two isatins, 1-methylisatin and 1-phenylisatin: a comparative study. J Phys Chem B. 2009 Nov 12;113 (45) :14904-13.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-W007719-01	7-Methylisatin
HY-18407-01	N-Methylisatoic anhydride
HY-N6838-01	1,1,1,1-Kestohexaose
HY-157129	AMPK-α1β1γ1 activator 1
HY-133623	1,1,1-Tribromoacetone
HY-149536	TWIK-1/TREK-1-IN-1
HY-W160628S	1,1,1-Trimethoxypropane-d5
HY-133630-01	1-Bromo-1,1-dichloroacetone
HY-W881439-01	1- (1,1-Dimethylethyl) tridecanedioate
HY-W032015S1	1-Bromooctane-1,1-d2

Alternative Products

Catalog	Name
TPL0252	1-Methylisatin
513015	5‐METHYLISATIN
FM38396-01	5-Methylisatin
sc-262932	7-Methylisatin
FM169139	1-methylisatin, 3-thiosemicarbazide
EDA56075	1-methylisatin, 3- (4-phenylthiosemicarbazide)
QLA83509	1-methylisatin, 3- (4-allylthiosemicarbazide)
FB70026-01	4-Bromo-7-methylisatin
OR7044-01	4-Bromo-5-methylisatin
sc-268022	5-Chloro-7-methylisatin

1-Methylisatin

Related Products

Alternative Products

Popular Products