MQA-P (TFA)

MQA-P (TFA)

• UNSPSC Description: MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO-, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO-, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images[1][2].
• Target Antigen: Fluorescent Dye
• Type: Dye Reagents
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/mqa-p-tfa.html
• Solubility: DMSO : 10 mg/mL (ultrasonic)
• Smiles: O=C([O-])C(F)(F)F.CN(C1=CC=C(C=C1)/C=C/C=C/C2=CC=[N+](C3=C2C=CC=C3)CC4=CC=C(C=C4)OP(C5=CC=CC=C5)(C6=CC=CC=C6)=O)C
• Molecular Weight: 720.72
• References & Citations: [1]Li Fan, et al. Multifunctional Fluorescent Probe for Simultaneous Detection of ONOO-, Viscosity, and Polarity and Its Application in Ferroptosis and Cancer Models. Anal Chem. 2023 Apr 4;95(13):5780-5787.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported