PRCC rabbit pAb

• Background:

  This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1) (p11; q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]

• Description:

  This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1) (p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. [provided by RefSeq, Aug 2010],

• UniProt:

  Q92733

• Swiss Prot:

  Q92733

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human PRCC AA range: 74-124

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB

• Concentration:

  1 mg/ml

• Dilution:

  WB 1: 500-2000

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  Nucleus .

• Gene ID (Human):

  5546