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Esaxerenone

CAT: 0804-HY-100471-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100471-01Size:1 mg
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Description
Esaxerenone (CS-3150) is a highly potent and selective non-steroidal mineralocorticoid receptor antagonist[1].
CAS Number
1632006-28-0
Product Name Alternative
CS-3150; XL-550
UNSPSC
12352005
Target
Mineralocorticoid Receptor
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Esaxerenone.html
Purity
99.93
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CN(CCO)C(C2=CC=CC=C2C(F)(F)F)=C1C)NC3=CC=C(S(=O)(C)=O)C=C3
Molecular Formula
C22H21F3N2O4S
Molecular Weight
466.47
References & Citations
[1]Yamada M, et al. Pharmacokinetics, distribution, and disposition of esaxerenone, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist, in rats and monkeys. Xenobiotica. 2017 Dec;47 (12) :1090-1103.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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